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人类LYCHOS的分子架构参与了溶酶体胆固醇信号传递

Qi Xiong1,2, Zhini Zhu3, Tingting Li2

  • 1The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Nature structural & molecular biology
|January 17, 2025
PubMed
概括

研究人员确定了 lysosomal胆固醇信号 (LYCHOS) 蛋白的高分辨率结构. 这揭示了其独特的融合架构,并为了解它如何感知胆固醇并激活mTOR信号提供了一个框架.

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