绝经后女性高平价体育活动与认知功能之间的关联:营养状况和抑郁症的链中介效应
Xiaotong Chen1, Kai Wei2, Shanshan Peng3
1Department of Laboratory Medicine, Jing'an District Central Hospital of Shanghai, Jing'an Branch Affiliated to Huashan Hospital, Fudan University, Shanghai, China.
身体活动有利于经更年期后妇女的认知功能,具有高平价 (≥3个分娩). 这些效应通过减少抑郁和改善营养状况来调解.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 神经科学是一个神经科学.
背景情况:
- 身体活动 (PA) 在绝经后妇女的认知效果不同,基于平价.
- 具有更高平价的女性在PA和认知功能之间表现出更强的联系.
- 在高平价女性中,这种关联的调解途径需要澄清.
研究的目的:
- 为了研究PA和认知功能之间的关联在中国的绝经后妇女队列中.
- 探索抑郁症和营养状况在这种关系中的调解作用.
主要方法:
- 对2296名绝经后妇女的横截面研究 (宝山区,2020年).
- 通过问卷和测量收集的数据 (人口统计,病史,生活方式,BMI,认知功能,营养,抑郁症).
- 采用了通用线性回归和链介导分析.
主要成果:
- 在高平价 (≥3个分娩) 的女性中,PA和认知功能之间发现了显著的积极关联.
- 在完全调整后,PA显著与认知功能相关 (β:0.795,95% CI:0.251-1.340,P <0.05).
- 连锁中介分析发现抑郁症和营养状况是显著的中介因素,占间接影响的37.96%.
结论:
- 身体活动对维持高平价的绝经后妇女的认知功能有好处.
- 抑郁症和营养状况是PA-认知功能关系中的关键调解因素.
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