在上部胃肠道内镜中进行前期治疗,以改善粘膜可视化. 一个系统的审查
Juan David Linares-Ramírez1, Andrea Carolina Córdoba1, Carlos Hernán Calderón-Franco1
1Department of Gastroenterology and Endoscopy, Colombia University Clinic, Bogotá, Colombia.
概括
使用西梅西康的前期治疗显著改善了上部肠道内镜检查期间的可视化. 这种安全有效的药物增强了内镜手术,尽管其他药物没有显著的益处.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 药理学 药理学是指药理学的学科.
背景情况:
- 上部胃肠内镜 (上部胃肠内镜) 的质量通常受到粘液导致的可视化不佳的限制.
- 建议先用粘菌剂和除泡剂进行预药,以增强可视化.
研究的目的:
- 评价使用粘液溶解剂和/或除泡剂进行前期治疗的疗效和安全性,以改善选择性上部肠道内镜检查期间的可视化.
主要方法:
- 随机对照试验的系统综述和来自Medline/Pubmed,Embase和Lilacs的系统综述.
- 进行元分析,以评估前期治疗药物对粘膜清除的疗效和安全性.
主要成果:
- 消泡剂和/或粘菌剂在选择性上部肠道内镜检查期间改善了胃的可见性.
- 与水相比,西梅西康和N-乙囊 (NAC) 显示出显著的改善.
- 单独使用西米西康和西米西康+NAC之间没有发现显著差异;其他药物没有显著的添加效应.
结论:
- 西梅西康是安全有效的改善可选上部肠道内镜的可视化.
- 使用其他药物或组合时,没有发现显著的可视化改善.
- 建议在处方医生的裁量范围内使用非标签的simethicone来增强内镜可视化.
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