Search research articles

关于 JoVE

概览领导团队博客 JoVE 帮助中心

作者

出版流程编辑委员会范围与政策同行评审常见问题投稿

图书馆员

用户评价订阅访问资源图书馆顾问委员会常见问题

研究

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments 存档

教育

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual 教师资源中心教师网站

使用条款与条件

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序

Same author

The GAPP Aggressivity Score Correlates with Total Enriched Somatic Variant Burden in Sporadic Pheochromocytoma-A Pilot Study.

Cancers·2026

Same author

Multiplatform curation in the development of ACMG/AMP specifications for Von Hippel-Lindau (VHL) disease.

Genetics in medicine : official journal of the American College of Medical Genetics·2026

Same author

Family History Predicts Primary Hyperparathyroidism Regardless of Genetic Predisposition.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026

Same author

RET Lys666Asn has a low rate of MEN2-related tumors but may be associated with pheochromocytoma.

Hormones (Athens, Greece)·2026

Same author

Pseudohypoxia and family history are key predictors of severe outcomes in hereditary pheochromocytoma and paraganglioma syndromes.

European journal of endocrinology·2026

Same author

Distinct epigenetic aging in sporadic and hereditary neuroendocrine neoplasms.

Clinical epigenetics·2026

Search research articles

相关实验视频

Updated: Jun 1, 2025

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models

Published on: March 13, 2018

关于1型多发性内分泌瘤的进展报告

Reut Halperin^1,2,3, Amit Tirosh^4,5,6

¹Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Familial cancer

|January 18, 2025

概括

多发性内分泌瘤1型 (MEN1) 综合征需要专业管理原发性甲状腺增多症和神经内分泌瘤,因为高风险和独特的疾病特征. 本报告详细介绍了MEN1患者目前的监测和治疗策略.

关键词:

甲状腺功能障碍症过高症.在这里,男人男人男人男人男人男人.神经内分泌瘤的神经内分泌瘤下垂体 - - 下垂体

更多相关视频

Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens

Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens

Published on: August 25, 2023

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

相关实验视频

Last Updated: Jun 1, 2025

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models

Published on: March 13, 2018

Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens

Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens

Published on: August 25, 2023

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

科学领域:

内分泌学在内分泌学.
遗传学是一个遗传学.
在瘤学瘤学.

背景情况:

多重内分泌瘤1型 (MEN1) 是一种与MEN1基因突变相关的自体主导性疾病.
患者面临高风险的原发性甲状腺功能增强症 (PHPT),垂体腺瘤和神经内分泌瘤 (NENs).
与MEN1相关的死亡率主要是由十二指肠-胰腺和胸膜NEN驱动的.

研究的目的:

提供关于MEN1综合征监测和管理的当前见解的概述.
讨论在MEN1患者中PHPT和NEN管理的具体考虑.
探索类似MEN1的演示和未来的研究方向.

主要方法:

对MEN1管理的当前文献和临床指导方针的审查.
分析PHPT和NEN在MEN1与零星病例中的管理差异.
讨论早期检测和干预的监测策略.

主要成果:

由于多腺干涉和多焦点瘤,MEN1管理需要针对PHPT (例如,近全副甲状腺切除术) 和NEN采取不同的方法.
终身NEN监测需要仔细规划,以平衡早期检测与最小化手术影响.
了解具有负遗传功能的MEN1类综合征至关重要.

结论:

有效管理MEN1综合征取决于针对其各种内分泌和瘤表现的量身定制的监测和治疗方案.
专业护理对于减轻与MEN相关的发病率和死亡率至关重要1.
需要进一步的研究来完善管理策略和理解非典型的呈现.