单双胞胎有胎液异常而没有TTTS的不良结果:一个案例对照研究
Cara Buskmiller1, Luis Delgadillo Chabolla1, Linda Alpuing Radilla1
1Baylor College of Medicine Houston TX, United States.
European journal of obstetrics, gynecology, and reproductive biology
|January 18, 2025
概括
即使不符合双胞胎输血综合征 (TTTS) 标准,单胆双胞胎 (MCDA) 双胞胎的胎液异常也表明风险增加. 这些怀孕面临更高的并发症,干预和胎儿死亡率.
科学领域:
- 周围生理学 周围生理学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 高风险的妇产科 高风险的妇产科
背景情况:
- 双胞胎双胞胎 (MCDA) 带来了独特的挑战,特别是在不符合双胞胎输血综合征 (TTTS) 诊断标准的情况下出现羊水异常时.
- 这些模两可的液体发现引起了临床医生和家庭对潜在不良结果的担忧.
- 了解这些边界异常的自然史对于适当的管理至关重要.
研究的目的:
- 描述不符合TTTS确定的标准的MCDA双胞胎胚胎液异常的自然史和临床意义.
- 为了确定这些怀孕的相关并发症和结果.
主要方法:
- 一项回顾性病例控制研究审查了2018-2022年MCDA双胞胎怀孕的超声波和临床记录.
- 患有不明原因的液体异常的病例被分类,不包括明显的TTTS,选择性胎儿生长限制 (sFGR),双胞胎贫血多细胞瘤序列 (TAPS),结构异常或扫描数据不足的病例.
- 为了比较,使用了一组在整个妊娠期间正常流体成像的对照组.
主要成果:
- 在140例患有非诊断性液体异常的病例中,与224例对照人群相比,观察到TTTS (41%),TAPS (8%) 的增加率,新的sFGR (11%) 和激光干预 (36%).
- 胎儿死亡发生在病例中更频繁 (11%对1%).
- 在病例组中,监视和早期分娩 (33.1 vs 35.1 周) 的孕产妇入院率也显著增加.
结论:
- 即使不符合TTTS标准,MCDA双胞胎的胎液异常也可以作为一个关键的警告信号.
- 这些发现与妊娠不良结果的显著更高风险有关,包括胎儿死亡和干预的需要.
- 对于表现出模两可的液体异常的MCDA双胞胎,需要密切监测和及时干预.
关键词:
一个钻石的子宫.胎儿生长限制 胎儿生长限制流体不一致性 流体不一致性流体不一致性 流体不一致性宫内生长限制 宫内生长限制激光 激光器 激光器 激光器这是一个单色体 (monochorionic).有氧化水的体.聚胺的多化物.双胞胎怀孕 双胞胎怀孕是什么意思双胞胎对双胞胎输血综合征更多相关视频
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