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Updated: Jun 26, 2026

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使用4-乙烯基环二氧化物的动物模型中的荷尔蒙波动:系统性审查和元分析

Aoi Mashimo1, Ryuga Oshida1, Yuichiro Oka2

  • 1Department of Health and Social Services, Health and Social Services, Graduate School of Saitama Prefectural University, Saitama, Japan.

Hormones and behavior
|January 18, 2025
PubMed
概括

4 - 乙烯基环二氧化物 (VCD) 动物模型通过诱导卵巢衰竭有效模仿更年期. 本综述详细介绍了VCD在老鼠和小鼠中的使用情况,证实了其在研究与更年期相关的荷尔蒙变化的有用性.

关键词:
这是女性荷尔蒙.动物模型 动物模型系统性审查 系统性审查乙烯基循环环烯基的使用.这是一个元分析.

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Hormonal Regulation01:40

Hormonal Regulation

Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
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Hormonal Regulation

The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
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Hormonal Regulation of the Menstrual Cycle

The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.