同时的多发性硬化和宫髓病:对患者报告结果的倾向匹配的QOD分析,以及在宫脊椎手术后恢复工作
Joseph Tingen1, Jainith Patel1, Hiba Hamid1
1Department of Neurosurgery, Tufts Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA.
Clinical neurology and neurosurgery
|January 18, 2025
概括
患有多发性硬化症 (MS) 的患者接受了宫骨髓病 (CM) 手术,报告的结果与没有MS的患者相似. 虽然MS患者的再入院率较高,但整体手术结果和患者报告的措施相似.
科学领域:
- 神经外科 神经外科
- 脊柱外科手术 脊柱外科手术
- 神经学 神经学
背景情况:
- 在多发性硬化症 (MS) 患者中,退行性宫骨髓病 (CM) 诊断是具有挑战性的,因为症状重叠和成像发现.
- 对于接受CM手术的MS患者,患者报告的结果测量 (PROM) 有有限的数据.
- 这项研究调查了CM的MS患者的外科治疗结果.
研究的目的:
- 为了比较MS患者和没有MS患者的术后PROM,这些患者接受了CM的选择性椎脊椎手术.
- 为了确定两个群体之间的并发症和恢复工作率的差异.
主要方法:
- 从质量结果数据库 (QOD) 获取的126名接受CM手术的患者的回顾性分析.
- 63名MS患者的年龄和性别与63名非MS患者相匹配.
- 对疼痛,部残疾指数 (NDI),满意度,并发症和手术后3个月和12个月恢复工作的视觉模拟量表 (VAS) 的比较.
主要成果:
- 这两个队伍的平均年龄 (57.9岁) 和性别分布 (63.5%的女性) 类似.
- 多发性硬化患者在基线时表现出较低的独立行走率 (p=0.014) 和较高的ASA等级 (p=0.018).
- 两组之间在VAS,NDI或满意度得分上没有发现显著差异;MS患者的3个月再录取率更高 (p=0.044) 但回归工作率相似 (>70%).
结论:
- 患者报告的结果 (PROM) 对于患有或没有多发性硬化症 (MS) 的宫骨髓病 (CM) 患者来说是可比的.
- 多发性硬化症患者经历了更高的3个月并发症率,尽管再入院大多与手术无关.
- 尽管存在诊断方面的挑战,但MS患者的CM手术结果与没有MS的患者相似.
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