瘤中的Gamna-Gandy体: 350次连续切除术的多机构临床病理学研究
Aysha Mubeen1, Richard Pacheco2, Mahmut Akgul2
1University of New Mexico, Albuquerque, NM, United States of America.
Annals of diagnostic pathology
|January 18, 2025
概括
在13%的脏瘤中发现了Gamna-Gandy体,硬化瘤结节,特别是清细胞细胞癌. 识别这些结构对于防止错误诊断为真菌感染至关重要.
科学领域:
- 腎病理學 腎病理學
- 在瘤学瘤学.
- 骨病理学 骨病理学
背景情况:
- 甘娜-甘迪体 (GG) 是一种主要在状细胞病患者的脏中发现的硬化性结节.
- 它们在组织中的存在很少被记录下来,主要是在病例报告中.
- 这项研究调查了瘤瘤切除术中GG体的发病率和特征.
研究的目的:
- 为了确定Gamna-Gandy体在脏瘤脏切除术的脏中的发生率.
- 分析与该队列中的GG体相关的临床病理特征.
- 强调区分GG体和其他病理发现的重要性.
主要方法:
- 对于3家针对瘤的医疗机构的瘤切除样本的回顾性审查.
- 详细记录临床病理特征和精确识别GG体.
- 由生殖尿路病理学家进行的组织病理学分析.
主要成果:
- 在13% (44/350) 的腎切除標本中,發現了Gamna-Gandy屍體.
- 清细胞细胞癌是与GG体 (40/44) 相关的最常见的瘤类型.
- GG体主要是内 (77%),多焦点 (57%),并与纤维化和化素相关.
结论:
- 加姆纳-甘迪体在瘤中相对常见,特别是清细胞RCC中.
- 形态意识至关重要,以避免误解GG体作为真菌或其他生物体.
- 这一发现强调了对脏瘤样本进行仔细的组织病理学评估的必要性.
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