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在耐火癌症患者中进行干预性临床试验的超急性排斥工程瘤病毒

Liping Zhong1, Lu Gan1, Bing Wang2

  • 1State Key Laboratory of Targeting Oncology, National Center for International Research of Biotargeting Theranostics, Guangxi Medical University, Nanning, Guangxi 530021, China.

Cell
|January 18, 2025
PubMed
概括

在癌症治疗的临床前和临床研究中,使用带有猪α1,3GT基因的纽卡斯尔病病毒的新型瘤病毒治疗显示出高安全性和有效性. 这种创新的免疫病毒疗法有望克服当前癌症治疗的局限性.

关键词:
的CRISPR肝癌模型临床试验有效性过敏的排斥免疫病毒治疗静脉内输入的NDV复合性纽卡斯尔病病毒耐火性癌症安全性α1,3GT 其他

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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