患有白内障手术并发症的风险 患者 之前内内注射疗法
Cindy S Zhao1, Kacper Chwialkowski1, Karen M Wai1
1From the Byers Eye Institute at Stanford Health Care (C.S.Z, K.C, K.M.W, P.M, E.R, E.B.K), Palo Alto, California, USA.
American journal of ophthalmology
|January 18, 2025
概括
之前的静脉注射 (IVI) 增加了白内障手术并发症的风险,特别是视网膜脱落 (RD). 这一发现凸显了在术前规划中考虑IVI病史的重要性,以获得更好的患者结果.
科学领域:
- 眼科医生 眼科 眼科
- 外科手术的结果
- 视网膜疾病 视网膜疾病
背景情况:
- 静脉内注射 (IVI) 是各种眼部疾病的常见治疗方法.
- 白内障手术是一种经常进行的手术,并发症率一般较低.
- 之前IVI对白内障手术结果的潜在影响尚未完全理解.
研究的目的:
- 为了比较白内障手术后并发症的发生率,在有和没有先前内注射 (IVI) 病史的患者中.
- 为了确定与先前IVI暴露相关的特定并发症.
- 为接受白内障手术的患者提供术前规划的信息,这些患者之前已经接受过IVI.
主要方法:
- 使用TriNetX研究网络进行的回顾性队列研究.
- 倾向性得分匹配 (PSM) 用于平衡群体之间的人口统计,系统和眼部并发症.
- 排除了以前进行了切除术或帕斯普拉纳视切除术 (PPV) 的患者.
主要成果:
- 在PSM之后,在白内障手术后90天内,与对照组相比,在先前IVI组 (3.3%) 观察到较高的综合并发症率 (2.4%).
- 之前的IVI组在手术后的30天和90天显示了视网膜脱落 (RD) 修复的风险增加.
- 虽然整体上不具有统计学意义,但IVI与90天糖尿病视网膜病变 (DR) 患者的前视镜切除率较高有关.
结论:
- 之前的静脉注射与白内障手术后并发症风险增加有关,主要是视网膜脱落.
- 眼科医生应在白内障手术的术前评估中考虑患者的IVI病史.
- 进一步的研究可能会探索特定的IVI药物或治疗方案以及它们对手术结果的差异性影响.
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