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相关概念视频

Kidney Structure01:45

Kidney Structure

68.7K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
68.7K
Nephrons01:10

Nephrons

2.1K
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
2.1K
External Anatomy of the Kidney01:21

External Anatomy of the Kidney

718
The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
718
Dialysis01:27

Dialysis

257
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
257
Internal Anatomy of the Kidney01:12

Internal Anatomy of the Kidney

1.3K
The kidneys are essential organs in the human body, performing a myriad of tasks that maintain homeostasis and overall health.
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
1.3K
Renal Corpuscle01:20

Renal Corpuscle

1.6K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
1.6K

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相关实验视频

Updated: Jun 1, 2025

Bilateral Renal Ischemia-Reperfusion Model for Acute Kidney Injury in Mice
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Bilateral Renal Ischemia-Reperfusion Model for Acute Kidney Injury in Mice

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急性损伤

Marlies Ostermann1, Nuttha Lumlertgul2, Rachel Jeong3

  • 1Department of Critical Care, King's College London, Guy's and St Thomas' NHS Foundation Trust, London, UK.

Lancet (London, England)
|January 18, 2025
PubMed
概括

急性损伤 (AKI) 是一个常见的疾病,在低收入国家发生率很高,导致严重的短期和长期健康后果. 有效的护理策略和长期随访模型需要进一步的研究和准确干预的子类型.

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科学领域:

  • 肝脏病学
  • 危急护理医学
  • 公共卫生

背景情况:

  • 急性损伤 (AKI) 是影响功能的一种普遍而复杂的疾病.
  • 在低收入和中等收入国家中, AKI 病例比较常见,
  • 短期影响包括增加死亡率,住院和医疗费用,而长期风险包括慢性病和心血管疾病.

研究的目的:

  • 审查目前对急性损伤 (AKI) 的理解.
  • 突出了细分类型的需要,以指导精确的干预.
  • 讨论目前和未来的治疗策略.

主要方法:

  • 现有关于AKI发病率,并发症和治疗的文献综述.
  • 分析当前的支持性护理策略和治疗方式.
  • 讨论关于AKI亚表型和长期随访的新证据.

主要成果:

  • AKI是一种多因素的疾病,具有显著的短期和长期不良结果.
  • 目前的AKI管理主要是支持性,专注于潜在的原因和并发症.
  • 越来越多的证据支持针对性治疗的AKI亚型的必要性.
  • 建议长期跟踪,但尚未建立最佳护理模式.

结论:

  • 急性损伤 (AKI) 具有显著的短期和长期健康风险,特别是在资源有限的环境中.
  • 以AKI亚表型为指导的精准医学方法对于改善患者的治疗结果至关重要.
  • 需要进一步的研究来确定AKI幸存者的有效长期护理模式.