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Updated: Jun 1, 2025

An Optimized Protocol for Electrophoretic Mobility Shift Assay Using Infrared Fluorescent Dye-labeled Oligonucleotides
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An Optimized Protocol for Electrophoretic Mobility Shift Assay Using Infrared Fluorescent Dye-labeled Oligonucleotides

Published on: November 29, 2016

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GATA4与Sox9增强剂mXYSRa/Enh13的结合对于小鼠的丸分化至关重要

Yuya Ogawa1,2,3, Iku Tsuchiya1,2, Shogo Yanai4

  • 1Department of Systems BioMedicine, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, Japan.

Communications biology
|January 18, 2025
PubMed
概括

在mXYSRa/Enh13增强剂中新发现的一种序列对于在小鼠中确定雄性性别至关重要. 对该序列的GATA4结合对于丸发育至关重要,并且需要SOX9表达.

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In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.  
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