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Updated: Jun 1, 2025

Examining Monosynaptic Connections in Drosophila Using Tetrodotoxin Resistant Sodium Channels
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在Drosophila RTK Sevenless (dROS1) 和GPCR BOSS之间相互作用的结构基础

Jianan Zhang1,2, Yuko Tsutsui1,2, Hengyi Li1,2

  • 1Department of Pharmacology, Yale University School of Medicine, New Haven, CT, 06520, USA.

Nature communications
|January 18, 2025
PubMed
概括

七无蛋白 (dROS1) 结构揭示了它如何与BOSS结合,这是Drosophila眼睛发育的关键步骤. 这项研究澄清了受体氨酸激酶 (RTK) 相互作用,并为研究人类ROS1,一种瘤基因提供了信息.

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