身体圆度指数与已婚女性不孕不育之间的非线性关联
Yong Fang1, Danfeng Ren1, Jinliang Pan1
1The First People's Hospital of Xiaoshan District, Hangzhou, 311200, China.
Scientific reports
|January 18, 2025
概括
身体圆度指数 (BRI) 的增加与20-45岁女性不孕症风险的增加密切相关. 建议保持健康的体重和腰围,以优化生育能力.
科学领域:
- 生殖健康 生殖健康
- 肥胖问题研究研究
- 诊断生物标志物 诊断生物标志物
背景情况:
- 肥胖,特别是内脏脂肪,越来越多地与不孕症有关.
- 身体圆度指数 (BRI) 量化了身体和内脏脂肪.
- 对于不孕症BRI的诊断价值需要进一步调查.
研究的目的:
- 调查BRI与已婚女性不育率之间的关联.
- 评估BRI在不孕症方面的诊断和预测能力.
主要方法:
- 分析了来自NHANES的1,305名已婚女性 (年龄在20-45岁) 的数据.
- 使用了后勤回归,平滑曲线拟合和ROC分析.
- 进行了单变量,多变量和子组分析.
主要成果:
- 一个单位的BRI增加与13%更高的不孕不育率相关 (OR=1.13).
- 较高的BRI与更高的不孕不育率 (OR=2.20) 有关.
- 观察到一种正面的非线性关系,BRI的拐点为7.95;BRI在年轻女性中显示出诊断潜力.
结论:
- 这项研究提供了第一个严格的证据,将增加的BRI与20至45岁女性中更高的不孕症患病率联系起来.
- 建议保持健康的体重和腰围,以提高生育能力.
- 将BRI整合到临床实践中可能有助于早期不孕症风险评估,尽管对老年人群需要进一步研究.
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