管道上的生物膜塑造了饮用水中的微生物组和抗生素耐药性
Wenfang Lin1, Keqian Zhao2, Qihui Wu3
1State Key Laboratory for Ecological Security of Regions and Cities, State Key Laboratory of Advanced Environmental Technology, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China.
Water research
|January 19, 2025
概括
饮用水系统中的生物膜含有抗生素耐药性基因 (ARG) 和病原体. 这项研究量化了它们在自来水中的增加,突出了生物膜中ARG的潜在健康风险.
科学领域:
- 环境微生物学环境微生物学
- 水质研究 水质研究
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 饮用水分配系统 (DWDS) 含有生物膜,可以保护病原体和抗生素耐药性基因 (ARG).
- 生物膜对自来水微生物群和抗体的确切影响以及相关的健康风险仍然不完全理解.
研究的目的:
- 研究DWDS中的生物膜如何影响微生物组成和自来水的抗生素耐药性.
- 量化评估受生物膜影响的自来水中的ARG与健康相关的风险.
主要方法:
- 生物膜反应堆使用市政饮用水运行了120天.
- 使用元基因组测序和组装来分析微生物群落和ARG.
- 转换分析和源追踪被用来评估ARG的流动性和贡献.
主要成果:
- 在生物膜,流水和废水之间观察到微生物组成的显著差异.
- 与流入的相比,ARG的丰度在生物膜和废水中增加,并确定了特定的致病宿主.
- 生物膜对废水的ARG概况做出了重大贡献,而ARG风险得分从流入到废水都显著增加.
结论:
- 生物膜的生长显著改变了自来水中的微生物群和抗生素耐药性.
- 在生物膜中增加的ARG水平和流动性会在DWDS中带来潜在的健康风险.
- 了解生物膜动态对于管理饮用水的水质和抗菌素耐药性至关重要.
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