与蓝色染料相比,使用印ocyanine绿色光剂进行尾逆向映射的可视化率更高
Sydney A Jupitz1, Christie Lin1, Tisha Kawahara1
1OnLume Surgical, Madison, Wisconsin.
The Journal of surgical research
|January 19, 2025
概括
与传统的蓝色染料相比,印ocyanine绿色 (ICG) 光与OnLume Avata系统在乳腺癌外科手术中为尾逆映射 (ARM) 提供了淋巴结构的优越可视化,有助于减少淋巴风险.
科学领域:
- 手术瘤学手术瘤学
- 医学成像医学成像
- 淋巴 edem 的研究研究.
背景情况:
- 在接受淋巴结手术的乳腺癌患者中,腹逆向映射 (ARM) 对于最大限度地降低淋巴风险至关重要.
- 目前对ARM的护理标准依赖于蓝色染料,在手术内可视化方面存在局限性.
- 近红外绿色 (ICG) 光成像为增强的手术内成像提供了一个有希望的替代方案.
研究的目的:
- 通过ARM的OnLume Avata系统评估使用ICG光的可行性.
- 为了比较ICG光与蓝色染料在ARM期间可视化淋巴结构的有效性.
主要方法:
- 八名乳腺癌患者接受了下淋巴结解剖和ARM.
- 使用ICG光和蓝色染料可视化淋巴细胞结构.
- 在OnLume Avata系统获得实时光图像切割前,手术期间和剖析后;定量分析包括对比度与噪声比,可视化率和信号与背景比.
主要成果:
- 与蓝色染料相比,ICG光提供了淋巴结,淋巴血管和淋巴结的优异可视化.
- 在八个案例中的七个案例中,在下附近的淋巴血管的切口前可视化得到了实现.
- 在整个ARM手术过程中,OnLume Avata系统的环境光兼容性促进了图像引导手术.
结论:
- 带有ICG光的OnLume Avata系统展示了对ARM的淋巴结构的卓越实时可视化.
- ICG光提供了改善的识别和可视化在蓝色染料与最小的干扰手术工作流程.
- 这项技术有可能提高手术精度,降低乳腺癌患者淋巴风险.
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