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动作VAD注册:一个集体的五年经验
Jonathan B Edelson1, Alexander Raskin2, Mohammed Absi3
1Division of Cardiology, Cardiac Center, the Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
概括
ACTION VAD注册表显示,儿科心室辅助器件 (VAD) 的使用情况有所改善,特别是在先天性心脏病 (CHD) 中. 需要进行进一步的研究,以提高年轻VAD患者的生存率和减少不良事件.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 机械循环支持 机械循环支持
- 遗传性心脏病是一种先天性心脏病.
背景情况:
- 先进的心脏疗法改善结果网络 (ACTION) 是一个协作学习健康系统,成立于2018年.
- 行动的重点是改善儿科心力衰竭患者的治疗结果,包括那些患有先天性心脏病 (CHD) 的患者,这些患者由心室辅助器件 (VAD) 支持.
研究的目的:
- 在ACTION VAD注册表中描述患者和设备特征.
- 报告儿科VAD接受者的1年植入后结果.
主要方法:
- 数据来自ACTION VAD注册表,涵盖2018年4月至2023年6月的数据.
- 该注册表包括1,430个VAD植入物在1,220名儿科患者 (≤18岁) 在57个北美地点.
主要成果:
- 男性占患者的55%;中位数年龄为3.7岁,36%的体重小于10公斤.
- 在近40%的患者中,先天性心脏病 (CHD) 是主要诊断,CHD VAD植入物从2018年的26%增加到2023年的42%.
- 支持的整体1年生存率为79.2%,中风发病率为13.7%. 婴儿的结果较差 (72.9%的生存率,20.8%的中风).
结论:
- 5年的ACTION VAD经验证明了在儿科VAD护理中日益增长的合作和不断发展的临床实践.
- 对于进一步提高生存率和减轻不良后果,特别是在年轻儿科患者群体中,急需进一步的进展.
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