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Updated: Jun 1, 2025

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设计,合成和选一个RNA优化化片段库的RNA优化片段库

Kasper P Lundquist1, Isabella Romeo1, Raffaele B Puglielli1

  • 1DTU Chemistry, Technical University of Denmark, Kgs. Lyngby 2800, Denmark.

SLAS discovery : advancing life sciences R & D
|January 19, 2025
PubMed
概括

这项研究开发了一个RNA优化的片段库用于药物发现,实现了针对RNA目标的更高的命中率. 建议提出指导方针,以推进基于fragment的RNA的配体发现,突出其治疗潜力.

关键词:
(19)F 核磁共振查 核磁共振查化学信息学是一种化学信息学.基于碎片的药物发现.这是一个RNARNARNARNARNA.

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RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
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