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Updated: Jun 1, 2025

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors
06:07

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors

Published on: August 5, 2022

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针对DNA的 thiazole-naphthyl衍生物的抗癌疗效:合成,晶体结构,密度功能理论,分子对接和分子动力学研究研究

Abhishek Aher1, Pradip Bera2, Paula Brandao3

  • 1Centre for DNA Fingerprinting & Diagnostics (CDFD), Hyderabad, Telangana 500 039, India.

International journal of biological macromolecules
|January 19, 2025
PubMed
概括

两种新型联体HL1和HL2显示出显著的抗瘤活性. 通过诱导亡,HL2表现出优越的DNA结合和对HepG2癌细胞的有效性,使其成为有前途的治疗候选者.

关键词:
它具有抗癌活性.分子对接是分子对接.分子动力学模拟模型纳夫塔利尼 纳夫塔利尼 纳夫塔利尼提亚醇 (Thiazole) 是一种可以在X射线晶体学.

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An In Vitro Enzymatic Assay to Measure Transcription Inhibition by GalliumIII and H3 5,10,15-trispentafluorophenylcorroles09:00

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