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Updated: Jun 1, 2025

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
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Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing

Published on: October 18, 2013

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一个对个体体质变异呼叫者和基于投票的集体进行对比研究,用于整个外体组序列的测序

Arnaud Guille1, José Adélaïde1, Pascal Finetti1

  • 1Predictive Oncology Laboratory, Marseille Research Cancer Center, INSERM U1068, CNRS U7258, Institut Paoli-Calmettes, Aix-Marseille University, Equipe labellisée « Ligue Nationale Contre le Cancer », 13009 Marseille, France.

Briefings in bioinformatics
|January 19, 2025
PubMed
概括

这项研究全面评估了20个体质变异呼叫者对整个外体序列测序 (WES) 数据的综合评估. 结合多个调用者的合并方法显著提高了检测单核酸变异 (SNV) 和癌症中的indels的准确性,提供了具有成本效益的解决方案.

关键词:
没有NGS,没有NGS.一个基准的基准指标.组合组合组合的组合组合.总的来说,一个团队就是一个团队.一个体质的体质.变体呼叫者变体呼叫者在投票中表决.

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