老年人营养风险指数与老年人心血管疾病之间的非线性关联基于NHANES数据库
Chengjun Li1, Yiyan Sun2, Hongyun Wu3
1Department of Neurology, Huangdao District Hospital of Traditional Chinese Medicine.
老年营养风险指数 (GNRI) 显示了与老年人心血管疾病的非线性联系. 营养状况影响心脏健康,影响因GNRI水平而异.
科学领域:
- 老年医学 老年医学
- 心血管健康 心血管健康
- 营养科学 营养科学
背景情况:
- 越来越多的证据将身体的营养状况与心血管疾病 (CVD) 的发展联系在一起,特别是在老年人中.
- 老年营养风险指数 (GNRI) 是一种临床工具,用于评估老年人的营养状况和风险.
- 了解营养对老年人心血管疾病的影响对于公共卫生至关重要.
研究的目的:
- 调查老年人群中GNRI和心血管疾病之间的关系.
- 评估GNRI测量的营养状况如何影响心血管疾病风险.
- 探索GNRI和CVD之间的潜在非线性关联.
主要方法:
- 使用国家健康和营养检查调查 (NHANES) 数据库 (2007-2018) 进行的横截面研究.
- 包括10277名60岁及以上的美国人.
- 权重多变量后勤回归和顺曲线分析了GNRI-CVD关联,并进行了子组分析.
主要成果:
- 经过对混因素进行调整后,GNRI和CVD之间没有统计学上显著的总体关联 (OR 0.98,95% CI 0.96-1.00).
- 顺的合曲线显示了GNRI和CVD之间的非线性相关性.
- 确定了一个转折点 (GNRI = 139.55);在此之前,GNRI与心血管疾病有负面关联,但在此之后没有显著关联.
结论:
- 在美国普通老年人群中,GNRI与心血管疾病之间存在非线性相关性.
- 根据GNRI的指标,营养状况与老年人心血管疾病风险有复杂的非线性关系.
- 进一步的研究可能会探索这种非线性关联对老年人心血管疾病预防策略的临床影响.
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