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Updated: Jul 27, 2026

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[在子宫内膜癌中分子分类和遗传表型特征的临床意义]

X W Wang1, J Lin1, H Chen1

  • 1Department of Pathology, China-Japan Friendship Hospital, Beijing100029, China.

Zhonghua zhong liu za zhi [Chinese journal of oncology]
|January 19, 2025
PubMed
概括

高吞吐量测序 (NGS) 有效地分类子宫内膜癌 (EC) 的分子亚型,揭示了显著的临床差异. 在MSI-H EC中进行进一步的基因分析可以指导个性化管理并改善患者的治疗结果.

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Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...