在经过皮肤冠状动脉干预的慢性全闭症患者中,甘油三指数和对比诱导的脏病之间的关联
Serdar Söner1, Adem Aktan2, Raif Kılıç3
1Department of Cardiology, Health Science University, Gazi Yaşargil Training and Research Hospital, Diyarbakır, 21070, Turkey. drserdar_89@hotmail.com.
BMC cardiovascular disorders
|January 19, 2025
概括
甘油三糖 (TyG) 指数与经过皮肤冠状动脉干预 (PCI) 进行慢性全闭症 (CTO) 的患者的对比诱导脏病 (CIN) 风险较高有关. 纳入TyG指数可能有助于防止CIN.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 代谢综合征是代谢综合征的一种.
背景情况:
- 三甘油糖 (TyG) 指数是胰岛素抵抗和心血管风险的指标.
- 对比诱导性脏病 (CIN) 是皮肤冠状动脉干预 (PCI) 后的一个显著并发症,特别是在慢性冠状动脉全封闭 (CTO) 患者中.
研究的目的:
- 调查TyG指数与CIN发生率和CTOPCI患者的死亡率之间的关联.
- 确定TyG指数是否可以作为该患者群体中CIN的预测指标.
主要方法:
- 分析了一组218名在2010年2月至2012年4月期间为CTO接受PCI的患者.
- 根据患者的TyG指数 (≥8.65和<8.65),患者被分为两组.
- 结果,包括CIN发展和死亡率,在96个月的随访期间进行了评估.
主要成果:
- 具有较高TyG指数 (1组) 的患者表现出明显更高的糖尿病和脂质失调率.
- 多变量分析确定了TyG指数作为CIN的独立预测因子 (OR=2.17,95%CI=1.21-3.89,P=0.009).
- 其他独立的CIN预测因素包括年龄,慢性病,外围动脉疾病和LVEF.
结论:
- 在接受PCI的CTO患者中,TyG指数和CIN患病率之间存在显著的相关性.
- 对于接受PCI的CTO患者,TyG指数可能是常规临床评估的宝贵补充,以帮助预防CIN.
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