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Updated: Jun 1, 2025

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
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了解和简化剂量检测:从剂量模拟到剂量估计

Dominic Bräm1, Freya Bachmann2, Johannes Schropp2

  • 1Pediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland.

Journal of clinical pharmacology
|January 20, 2025
PubMed
概括

本研究介绍了OptiDose,这是一种先进的剂量估计方法,通过有效地确定患者群体的最佳治疗剂量来简化药物开发. 它超越了耗时的模拟,以确保满足安全性和有效性要求.

关键词:
最佳剂量 优化剂量剂量估计剂量估计发现剂量发现剂量治疗剂量的治疗剂量.

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