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Updated: Jun 12, 2026

Fluorescence-quenching of a Liposomal-encapsulated Near-infrared Fluorophore as a Tool for In Vivo Optical Imaging
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少是多:在NIR-IIb窗口中进行生物成像的稳定分子染料的捐赠工程

Tianbao Wang1,2, Yufei Qin1,3, Jin-Yu Wang1

  • 1Center for Advanced Materials Research & Faculty of Arts and Sciences, Beijing Normal University, Zhuhai 519087, China.

Journal of medicinal chemistry
|January 20, 2025
PubMed
概括

研究人员开发了一种新的小分子染料DA-5,用于近红外IIb (NIR-IIb) 光成像的增强清晰度. 这种染料使各种生物系统的高性能可视化成为可能,进步了体内生物光学.

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相关概念视频

Total Internal Reflection Fluorescence Microscopy01:05

Total Internal Reflection Fluorescence Microscopy

Total internal reflection fluorescence microscopy or TIRF is an advanced microscopic technique used to visualize fluorophores in samples close to a solid surface with a higher refractive index, such as a glass coverslip. TIRF only allows fluorophores in proximity to the solid surface to be excited. When light from a medium with a lower refractive index (such as air) hits the glass coverslip at a critical angle, the light undergoes total internal reflection stead of passing through the glass.