RXRα/PPARγ/NEDD4SASP

Yinghong Zheng1,2, Jiayuan Kou3, Xi Gao2

  • 1Department of Pharmacology, Tianjin Medical University 22 Qixiangtai Road, Heping District, Tianjin 300070, P. R. China.

概括

柏柏林 (BBR) 通过向RXRα/PPARγ/NEDD4通路来对抗动脉样硬化中的衰老细胞炎症. 这种天然化合物可以减少老化相关的分泌表型 (SASP) 和小鼠模型中的斑块进展.

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