坚固粘附和高机械强度的水凝,可以有效地粘附湿组织
Chenyang Li1, Yang Qian1, Xueping Zhang1
1Key Laboratory of Textile Science & Technology, Ministry of Education, College of Textiles, Donghua University, Shanghai, 201620, China. xpzhang@dhu.edu.cn.
Journal of materials chemistry. B
|January 20, 2025
概括
这项研究引入了一种新的生物粘合水凝用于伤口关闭,证明了优越的湿粘和机械强度. 开发的水凝为有效的伤口愈合提供了一个有希望的,最少侵入性的解决方案.
科学领域:
- 生物材料科学 生物材料科学
- 聚合物化学 聚合物化学
- 伤口愈合技术 伤口愈合技术
背景情况:
- 生物粘合性水凝由于最小侵入性应用,对伤口关闭充满希望.
- 现有的水凝往往在湿组织上缺乏粘附性和机械完整性.
研究的目的:
- 开发一种准备使用的生物粘合水凝,具有增强的湿粘性和机械性能,用于伤口关闭.
- 调查新型水凝的粘附机制和材料特性.
主要方法:
- 酸 (AA),甲基醇功能化奇托 (C-CS) 和酸N-氧苏胺乙烯 (AA-NHS乙烯) 的单紫外线交联聚合.
- 在膨胀状态下,水凝的机械性能 (拉伸强度,断裂应变,性) 的表征.
- 对湿猪皮的粘合性能 (剪切强度,界面性,破裂压力) 的评估.
主要成果:
- 这种PAA-NHS/C-CS水凝具有很高的抗拉强度 (~630kPa),破裂应变 (~1950%) 和性 (~4250kJ m−3).
- 在潮湿的猪皮上实现了高剪切强度 (~160 kPa),界面性 (~630 J m-2),以及破裂压力 (~447 mmHg).
- 通过键,静电吸引力和双粘合部分 (NHS和甲基醇组) 证明了强大的粘附性.
结论:
- 开发的PAA-NHS/C-CS水凝为伤口关闭提供了一个有前途的解决方案,具有快速,强大的粘合力和高机械强度.
- 先进的材料特性和易于使用的组合使得这种水凝适合于伤口管理中的临床应用.
相关概念视频
Adhesion
Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules.
Capillary action is a result of water’s adhesive tendencies. When a narrow glass...
Capillary action is a result of water’s adhesive tendencies. When a narrow glass...
Cohesion
Cohesion is the attraction between molecules of the same type, such as water molecules. Water molecules have an overall neutral charge but are polar molecule. An oxygen atom in one water molecule has a partial negative charge that can bind to a hydrogen atom with a partial positive charge in a second water molecule, forming a hydrogen bond. Each water molecule can form up to four hydrogen bonds with other water molecules. Hydrogen bonds are responsible for water's cohesive nature.
On a surface,...
On a surface,...
Mortar Properties
Mortar properties encompass a range of characteristics crucial for construction and masonry work, including workability, water retention, bond strength, durability, compressive strength, volume change, and appearance. Workability refers to mortar's ability to be easily applied and manipulated without sagging or falling off surfaces, which is important for efficient masonry unit placement and alignment. Water retention is essential to prevent the mortar from losing moisture too quickly to the...


