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Updated: Jun 1, 2025

A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds
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A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds

Published on: April 6, 2016

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作为表皮生长因子受体抑制剂的新型Eyne-modified 1,4-thiazepines:抗癌和计算研究

Harika Atmaca1, Çisil Çamlı Pulat2, Suleyman Ilhan1

  • 1Department of Biology, Faculty of Engineering and Natural Sciences, Manisa Celal Bayar University, 45140 Manisa, Turkey.

ACS omega
|January 20, 2025
PubMed
概括

新型enyne修饰的1,4-thiazepines (TZEPs) 显示出强大的抗癌作用. TZEP7有效诱导亡并抑制EGFR,在癌症治疗中显示出显著的前景.

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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

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