评估初级保健医生对药物遗传学的知识,感知和实践
Emily K Johengen1, Kristen M Ward1,2, Antoinette B Coe2
1Michigan Medicine, Ann Arbor, Michigan.
Journal of the American College of Clinical Pharmacy : JACCP
|January 20, 2025
概括
初级保健临床医生很少订购药物遗传学 (PGx) 测试,但他们对药剂师支持解释结果感兴趣. 大多数临床医生对PGx测试解释缺乏信心,强调需要教育和药房服务.
科学领域:
- 药物遗传学和精准医学 药物遗传学和精准医学
- 主要护理实践的初级护理实践
- 临床药房服务 临床药房服务
背景情况:
- 药物遗传学 (PGx) 测试越来越容易获得,但其融入初级保健机构以及药剂师在临床医师教育中的作用仍然未得到充分探索.
- 关于初级保健临床医生如何利用,记录和根据PGx测试结果采取行动的研究有限.
研究的目的:
- 评估PGx测试在初级保健诊所的使用情况.
- 确定当前临床医生记录和响应PGx测试结果的实践.
- 为了衡量临床医生对PGx教育和药剂师咨询服务的兴趣.
主要方法:
- 一项16项调查通过电子邮件发送给一个学术医疗中心的医生,医生助理,护士从业人员和初级保健药剂师.
- 用描述性统计数据分析了关于PGx测试订单,解释舒适性,文档和教育需求的调查数据.
主要成果:
- 该调查实现了15.8%的响应率 (n=55),主要是医生 (84%).
- 近40%的受访者报告说患者呈现PGx结果,与仅有9%的人订购测试形成鲜明对比. 文档是可变的,52%的患者根据结果没有改变治疗方法.
- 显著多数 (96%以上) 的人对解释PGx结果缺乏信心,但80%的人表示愿意咨询PGx培训的药剂师.
结论:
- 初级保健临床医生更有可能通过患者介绍而不是通过直接订购来遇到PGx结果.
- 临床医生对PGx测试解释的信心和能力存在显著的差距.
- 对PGx教育有很大的兴趣,对药剂师主导的咨询服务有很明显的需求,以支持初级保健机构的临床医生.
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