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对Aβ-的结构多样性的调查:分子动力学方法

Anna P Tolstova1, Alexei A Adzhubei1,2, Maria A Strelkova1

  • 1Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, 119991 Moscow, Russia.

Biophysical reviews
|January 20, 2025
PubMed
概括

分子动力学 (MD) 有助于建模β-粉样蛋白 (Aβ),内在无序蛋白 (IDP). 本综述详细介绍了Aβ单体和聚合结构的MD方法,包括一般的IDP建模方法.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.这是一种β-粉样,β-粉样.本质上是无序的蛋白质.分子动力学分子动力学蛋白质聚合蛋白质的聚合.蛋白质折叠过程中的蛋白质折叠

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