酒精使用与过度活跃膀疾病之间的关系:NHANES 2005-2016年的横截面研究
1Department of Urology, Xijing Hospital, Air Force Medical University, Xi'an, China.
Frontiers in public health
|January 20, 2025
概括
与不饮酒相比,中度至重度的酒精消费与过度活性膀综合征 (OAB) 的风险较低. 这表明酒精可能不是OAB症状的长期风险因素.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 过度活性膀综合征 (OAB) 显著影响生活质量和日常功能.
- 酒精的利尿性质可能会加剧OAB症状,如尿急和尿频.
- 之前关于酒精消费和OAB的研究已经产生了相互矛盾的结果.
研究的目的:
- 调查酒精消费模式与OAB症状之间的关系.
- 利用一个庞大的,具有全国代表性的数据集来分析这种关联.
主要方法:
- 对2005-2016年国家健康和营养检查调查 (NHANES) 数据的分析.
- 利用过度活跃的膀症状量表 (OBSS) 来识别OAB病例.
- 采用多变量逻辑和顺序逻辑回归来评估与OAB发病和严重程度相比,酒精使用频率和数量.
主要成果:
- 在加权样本中,12.4%的人报告了OAB;不饮酒的人显示OAB风险更高.
- 在调整后,较高的酒精消费 (10+饮料/月) 与较低的OAB风险显著相关.
- 适度饮酒 (第二和第三四分位数) 也显示出与降低OAB风险的显著关联.
结论:
- 酒精消费与OAB的发病率有显著的相关性.
- 研究结果表明,酒精可能不是OAB的长期风险因素.
- 需要进一步的临床试验来确认酒精消费是OAB的潜在干预目标.
相关概念视频
Substance Use Disorders Affecting Sleep
158
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
158
Disorders of the Urinary System
229
The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
229
The Micturition Reflex
412
Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying.
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
412
Drugs for Treatment of Diarrhea-Predominant IBS
145
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
145
Stress Prevention and Stress Management Techniques IV
25
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
25
Disorders of the Autonomic Nervous System
536
The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's...
Raynaud's disease, also known as Raynaud's...
536


