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非心脏大手术后的急性损伤:它是否减少了?

Jeong Min Cho¹, Soie Kwon^2,3, Sunah Yang^4,5

¹Department of Internal Medicine, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong, Republic of Korea.

Clinical kidney journal

|January 20, 2025

概括

手术后急性损伤 (PO-AKI) 的发生率已经下降,但严重的PO-AKI (S-PO-AKI) 率保持不变. 这表明,虽然整体PO-AKI正在下降,但关键病例需要持续关注和干预.

科学领域:

腎臟病學 (nephrology) 是一種醫學專業.
外科手术的结果
公共卫生公共卫生

背景情况:

在临床实践中强调了术后急性损伤 (PO-AKI) 的识别和预防.
关于PO-AKI发病率的实际趋势存在不确定性.
调查PO-AKI的时间变化对于患者护理至关重要.

研究的目的:

分析PO-AKI发生率随时间的变化.
确定影响PO-AKI利率变化的因素.
评估严重的PO-AKI (S-PO-AKI) 趋势的发生率.

主要方法:

对138,235名接受非心脏重大手术的患者 (2005-2020年) 的回顾性分析.
术后7天内根据KDIGO标准定义的PO-AKI;S-PO-AKI作为第二或第三阶段.
结点回归和多变量逻辑回归用于时间分析.

主要成果:

整体PO-AKI发生率从8.6%降至5.1% (APC -4.2%).
严重的PO-AKI (S-PO-AKI) 发病率保持在0.8%-0.9% (APC0.9%) 的稳定水平.
最近的外科手术患者年龄较大,患病并发症较多,基线PO-AKI风险较高.

结论:

尽管患者风险因素增加,PO-AKI的发病率却有所下降.
严重PO-AKI的发病率没有显示出类似的下降.
尽管总体趋势,仍需要对严重的PO-AKI保持持续警.

关键词:

急性脏损伤急性脏损伤肌氨酸是什么意思肌氨酸是什么意思流行病学因素流行病学因素这是一个运营性的行动.手术手术手术手术手术手术手术手术手术

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