补充C4,习惯性便秘和睡眠障碍之间的关联在中国最年长和百岁的成年人中
Zhigao Sun1, Yan Nie2, Jianqiu Pei3
1Traditional Chinese Medicine Department, Hainan Hospital of Chinese People's Liberation Army General Hospital, Sanya, People's Republic of China.
Journal of inflammation research
|January 20, 2025
概括
睡眠障碍与较低的补充C4水平和老年中国成年人习惯性便秘的更高率有关. 这些发现表明,通过准免疫因素和肠道健康,对睡眠问题的潜在新疗法.
科学领域:
- 老年学是一门学科.
- 免疫学 免疫学 免疫学
- 胃肠病学 胃肠病学
背景情况:
- 睡眠障碍被认为是一种与免疫系统相关的疾病.
- 肠-大脑轴在调节睡眠方面发挥着至关重要的作用.
- 了解免疫功能,肠道健康和睡眠之间的相互作用对公共健康至关重要.
研究的目的:
- 调查补充C4,习惯性便秘和睡眠障碍之间的关联.
- 为预防和治疗老年人睡眠障碍提供参考.
主要方法:
- 使用来自中国海南百岁老人队列研究的数据进行横截面研究.
- 使用匹兹堡睡眠质量指数 (PSQI) 评估睡眠质量.
- 补充C4水平通过酶色度测量和习惯性便秘通过肠道健康问卷.
主要成果:
- 总共有1621名参与者被纳入;30.41%的人经历了睡眠障碍.
- 睡眠障碍患者的补充C4水平显著降低,习惯性便秘的患病率更高.
- 补充C4与PSQI得分有负相关性,而习惯性便秘与PSQI得分有积极相关性.
结论:
- 睡眠障碍与补充C4负相关,与老年中国成年人的习惯性便秘正相关.
- 这些发现扩大了关于肠-大脑轴与老年人睡眠相关的知识.
- 建议潜在的睡眠障碍治疗策略,包括免疫因子调节和肠道功能管理.
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