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在患有良性基本白血的患者中评估视网膜和胸腔微血管性
Husna Topcu1, Fatma Poslu Karademir2, Mehmet Goksel Ulas2
1Department of Ophthalmology, Osmangazi Aritmi Hospital, Bursa, Turkey.
Current eye research
|January 20, 2025
概括
良性基本血栓 (BEB) 与视网膜微血管结构的改变有关,显示了血管密度增加和较小的状血管区域. 这些变化可能表明BEB患者的潜在血管变化.
科学领域:
- 眼科医生 眼科 眼科
- 神经眼科神经眼科
- 血管生物学 血管生物学
背景情况:
- 良性基本血栓 (BEB) 是一种影响眼肌肉的神经运动障碍.
- 在BEB患者中,视网膜和胸膜的微血管变化尚不清楚.
研究的目的:
- 为了评估BEB患者的视网膜和冠状腺微血管变化.
- 确定影响BEB微血管变化的因素.
主要方法:
- 光学连贯断层扫描血管造影 (OCTA) 用于检查16名BEB患者和20名对照.
- 测量包括黄斑血管 perfusion 密度 (VPD),状血管区域 (FAZ) 和亚状冠状腺厚度 (CT).
- 收集了关于肉毒素A (BTx-A) 使用的回顾性数据.
主要成果:
- 与对照组相比,BEB患者在表面和深部黄斑毛细管中显示出明显不同的VPD (p<0.05).
- 在BEB患者的胆囊层中观察到增加的VPD (p<0.05).
- BEB组的表面和深层FAZ值显着较小 (p<0.05) 和较薄,尽管在统计学上没有显著意义,胸膜厚度 (p=0.138).
结论:
- BEB与表面和深层毛细管的视网膜血管密度增加有关.
- 在BEB患者中观察到减少的状血管区域区域.
- 在BTx-A剂量和OCTA参数之间没有发现相关性.
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