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Updated: Jun 10, 2026

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在三种癌症中对内和外周BCR谱的系统评估

Sofia V Krasik1,2, Ekaterina A Bryushkova2,3,4, George V Sharonov2,3,5

  • 1Center of Life Sciences, Skolkovo Institute of Science and Technology, Moscow, Russian Federation.

eLife
|January 20, 2025
PubMed
概括

癌症瘤对B细胞的影响不同于健康组织. 这项研究揭示了瘤中独特的B细胞受体特征,表明瘤微环境 (TME) 中的发育和选择过程发生了变化.

关键词:
在BCR中,BCR是指BCR.癌症生物学 癌症生物学人类 人类 人类 人类 人类 人类 人类过度突变是一种超级突变.免疫球蛋白是一种免疫球蛋白.免疫学 免疫学 免疫学这是一种炎症炎症炎症炎症.瘤透到B细胞中.

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Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...