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Updated: Jul 14, 2026

Fluorescence-quenching of a Liposomal-encapsulated Near-infrared Fluorophore as a Tool for In Vivo Optical Imaging
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开发离线近红外光探针,用于对粉样β物种进行敏感的体内成像,具有增强的药理动力学

Qingchen Liu1, Yiming Men2, Daqing Fang3

  • 1School of Pharmacy, China Pharmaceutical University, Nanjing, 211198, China.

Chemistry (Weinheim an der Bergstrasse, Germany)
|January 20, 2025
PubMed
概括

研究人员开发了两种新的近红外 (NIR) 光探针用于阿尔茨海默病 (AD) 诊断. 在AD模型小鼠中,NIR-1在检测β-粉样蛋白 (Aβ) 中表现出卓越的性能,显示出高灵敏度和快速进入大脑.

关键词:
阿尔茨海默氏症的疾病是阿尔茨海默氏症.Aβ 种类 Aβ 种类在生物体内检测检测.NIR光探测器进行光探测.药物动力学 药物动力学

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...