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Updated: Jun 1, 2025

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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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含有英多尔部分的皮拉姆类似物:合成,生物活性和分子对接研究

Zhitian Huang1, Qianyu Huang1, Hong Wei1

  • 1Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai, People's Republic of China.

Molecular diversity
|January 20, 2025
PubMed
概括

研究人员开发了一种新型的含有醇的杀虫剂,向糖酸脱酶 (SDH),以对抗线虫耐药性. 一些类似的药物表现出与商业杀虫剂相当的活性,为药物开发提供了一个有希望的新模板.

关键词:
同性学建模的模拟.印度尔 (Indole) 是一种分子对接是分子对接.类杀虫活动 类杀虫活动SDH SDH SDH SDH SDH SDH SDH SDH SDH SDH SDH SDH SDH SDH SDH SDH SDH

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