怀孕并发症和长期动脉样硬化心血管疾病风险
Soniya V Rabadia1, Sarah Heimberger2, Natalie A Cameron3
1Department of Medicine, Division of Cardiology, University of California, Los Angeles, Los Angeles, CA, USA.
妊娠并发症,如妊娠高血压疾病,与更高的长期动脉样硬化心血管疾病 (ASCVD) 风险有关. 医疗保健提供者应考虑生殖史,以准确评估心血管风险.
科学领域:
- 心血管健康 心血管健康
- 生殖医学 生殖医学
- 公共卫生 公共卫生
背景情况:
- 妊娠并发症,包括妊娠高血压障碍 (HDP),越来越多地被认为是长期心血管疾病的重要风险因素.
- 健康的社会决定因素在不良妊娠结果 (APO) 和随后的动脉样硬化心血管疾病 (ASCVD) 风险的流行中发挥着至关重要的作用.
- APO与短期和长期ASCVD风险有关,而HDP具有最高风险.
研究的目的:
- 讨论怀孕并发症与长期动脉样硬化心血管疾病 (ASCVD) 风险之间的关系.
- 探索APO和ASCVD之间的关联背后的机制.
- 强调将生殖健康史纳入心血管风险评估的必要性.
主要方法:
- 审查关于妊娠并发症和ASCVD风险的现有研究.
- 分析健康的社会决定因素对APO和ASCVD的影响.
- 评估当前的ASCVD风险模型及其局限性.
主要成果:
- 怀孕并发症和ASCVD风险增加之间存在强烈的联系,包括微血管冠心病.
- 妊娠高血压障碍 (HDP) 与APO中最高的ASCVD风险有关.
- 关于APO对ASCVD的因果关系与标志物地位的争论正在进行中.
结论:
- 当前的ASCVD风险预测模型不考虑怀孕并发症史.
- 医疗保健提供者必须获得生殖健康史,以准确地向患者提供关于长期心血管风险的建议.
- 非侵入性查工具,如冠状动脉评分,可能有助于风险分层,但需要进一步研究.
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