晚年孕产妇怀孕的出生结果
Jana Diabelková1, Erik Dorko1, Kvetoslava Rimárová1
1Department of Public Health and Hygiene, Faculty of Medicine, Pavol Jozef Safarik University in Kosice, Kosice, Slovak Republic.
Central European journal of public health
|January 20, 2025
概括
先进的孕产妇年龄 (35-39岁) 和非常先进的孕产妇年龄 (≥40岁) 与增加妊娠不良结果的风险有关. 这包括更高的早产率,剖腹产和新生儿的Apgar分数较低.
科学领域:
- 产科和妇科 产科和妇科
- 围产儿医学 围产儿医学
- 生殖健康 生殖健康
背景情况:
- 在全球范围内,晚年孕产妇 (35岁及以上) 怀孕越来越普遍.
- 这种人口变化需要清楚地了解相关的孕产妇和产周风险.
研究的目的:
- 描述晚期孕产妇年龄 (35-39岁) 和非常晚期孕产妇年龄 (≥40岁) 的妇女的孕产妇和产周结果.
- 将这些结果与年轻母亲 (20-34岁) 的对照组进行比较.
主要方法:
- 对2300个单独出生 (2020-2021) 的回顾性队列研究.
- 组:对照组 (20-34岁),晚产期 (35-39岁),非常晚产期 (≥40岁).
- 排除标准包括多胎妊娠,吸烟,酒精使用,胎儿形,子宫内胎儿死亡和出生体重≤500g.
主要成果:
- 随着母亲的晚年,早产 (p=0.004) 和非常早产 (p=0.010) 的统计显著增加.
- 较高的剖腹产率 (p<0.001),非常低的出生体重 (p=0.027) 和极低的出生体重 (p=0.001) 被注意到.
- 在5分钟的Apgar分数较低 (<7,p=0.020) 也与晚年母亲年龄有显著的关联.
结论:
- 先进的孕产妇年龄是不良妊娠结果的显著预后因素.
- 35岁及以上的妇女在怀孕和分娩期间面临更高的并发症风险,这会影响母亲和婴儿的健康.
相关概念视频
02:07Oogenesis
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
02:57Meiosis vs. Mitosis
Cell division is necessary for growth and reproduction in organisms. Mitosis aids cell growth and development by dividing somatic cells. In contrast, meiosis causes the division of germ cells and plays an essential role in sexual reproduction. Due to their unique functional requirements, mitosis and meiosis differ from each other in multiple aspects.
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
01:07Teratogenicity
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
01:28Menopause
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
01:22Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption
As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
01:19Mitral Valve Prolapse III: Nursing Management
The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...