使用FRAX和FRAXplus评估骨折风险
Teck H A Tan1,2, Helena Johansson3,4, Nicholas C Harvey5,6
1Fast and Chronic Programmes, Alexandra Hospital, Singapore.
概括
骨折风险计算器FRAX®通过提供个性化的10年骨折概率来改善骨质疏松症的管理. FRAXplus®通过基于网络的限制调整来增强治疗决策.
科学领域:
- 骨质疏松症管理管理
- 骨折风险评估 骨折风险评估
- 临床决策支持 临床决策支持
背景情况:
- FRAX® (骨折风险评估工具) 在2008年推出.
- 在骨质疏松症管理的全球指南中广泛采用.
- 提高骨折风险预测,而不仅仅是骨矿物质密度.
研究的目的:
- 审查FRAX®的开发和应用.
- 将FRAX®疗效与仅仅骨矿物质密度进行比较.
- 讨论FRAX®的限制和拟议的调整.
主要方法:
- 探索FRAX®的开发和改进.
- 干预和评估值的分析.
- 对算术调整和FRAXplus®的审查.
主要成果:
- FRAX®提供个性化的10年骨折概率.
- 将FRAX®整合到指南中,有助于骨质疏松症的管理.
- FRAXplus®提供了一个基于网络的平台,用于增强决策.
结论:
- FRAX®显著提高了骨折风险预测.
- 通过调整来解决FRAX®的局限性,可以提高效用.
- FRAXplus® 便于更容易的应用和更好的治疗决策.
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