全球线性加速器的要求和个性化的国家建议:一个横截面,基于人口的研究
Fabio Y Moraes1, Andre G Gouveia2, Vanessa Freitas Bratti3
1Department of Oncology, Queen's University, Kingston, ON, Canada; Division of Cancer Care and Epidemiology, Cancer Research Institute, Queen's University, Kingston, ON, Canada.
The Lancet. Oncology
|January 20, 2025
概括
线性加速器短缺指数 (LSI) 揭示了全球辐射疗法短缺,特别是在低收入国家. 迫切需要投资来解决这些差异,并满足到2045年的未来线性加速器 (LINAC) 需求.
科学领域:
- 在瘤学瘤学.
- 医学物理 医学物理
- 公共卫生 公共卫生
背景情况:
- 线性加速器短缺指数 (LSI) 量化了线性加速器 (LINAC) 需求与放射治疗可用性的比例.
- 对LINAC分发和放射治疗需求的全球评估对于公平的癌症护理至关重要.
- 在全球范围内,LINAC接入的差异对癌症治疗结果产生了重大影响.
研究的目的:
- 使用LSI来预测全球LINAC需求.
- 根据其辐射治疗短缺程度 (LINAC短缺等级) 将国家分类.
- 预测未来对放射治疗基础设施的投资需求.
主要方法:
- 一项基于人口的横截面研究分析了181个国家的国家级数据.
- LINAC的分销,放射治疗中心,癌症发病率,GDP和人均国内生产总值均来自全球数据库.
- 计算了LSI (LINAC使用/450*100),并根据短缺严重程度对国家进行了分级 (0-4).
主要成果:
- 全球LSI中位数为130,表明放射治疗能力不足30%.
- 低收入国家出现了最严重的短缺 (中位数为LSI 1523),其中20%没有LINAC.
- 据估计,到2045年,需要30,470个LINAC,这需要大量投资,特别是在LMICs.
结论:
- LSI和LINAC缺乏度等级是评估和预测放射治疗需求的有效工具.
- 全球辐射治疗可用性的巨大差异迫切需要对能力建设进行投资.
- 针对低收入和中等收入国家进行有针对性的投资对于解决放射治疗缺口至关重要.
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