相关实验视频

Updated: Jun 1, 2025

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

早期生活中的空气污染和系统性免疫生物标志物:系统性审查

Veronica Carvajal¹, Juan Vicente Jorques Molla², Yana Luo¹

¹ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), Spain.

Environmental research

|January 20, 2025

概括

儿童暴露于空气污染可能会影响他们的免疫系统,但证据有限. 需要更多的研究来了解室内和环境空气污染对儿童免疫生物标志物的影响.

科学领域:

环境健康环境健康
免疫学免疫学免疫学
儿科儿科儿科

背景情况:

儿童在发育中的免疫系统容易受到空气污染的影响,增加了不良健康结果的风险.
将空气污染与年轻人的免疫失调联系在一起的机制仍然不太清楚.
对早期空气污染和免疫生物标志物的流行病学证据的系统审查.

研究的目的:

系统地审查有关室内和环境空气污染对儿童 (出生至18岁) 系统性免疫生物标志物影响的流行病学证据.
识别有关空气污染对生命早期免疫力影响的知识差距.

主要方法:

在PubMed,SCOPUS和Web of Science中按照PRISMA指南进行系统的文献搜索,直到2024年8月10日.
定义了研究检索和质量评估的包含/排除标准.
五位独立审查员进行了审查过程.

主要成果:

有限的证据表明,产前PM2.5暴露可能会减少T细胞 (CD3+,CD8+).
产后的PM暴露与IgE增加或过敏敏感性有有限的关联.
由于研究的局限性和不一致性,对其他暴露结果组合的证据不足,特别是室内空气污染 (12项研究).

结论:

显著需要进一步研究空气污染对儿科免疫系统的影响.
为未来的研究提供了建议,以阐明生物途径和免疫反应.
鉴于终身健康影响和全球暴露负担,优先考虑儿童免疫和空气污染的研究至关重要.

关键词:

空气污染大气污染生物标志物生物标志物孩子孩子孩子孩子免疫系统的免疫系统.婴儿婴儿婴儿婴儿婴儿婴儿年轻人年轻人年轻人年轻人年轻人

更多相关视频

Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters

Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters

Published on: July 12, 2024

Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India

Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India

Published on: December 23, 2022

相关概念视频

Asthma-I: Introduction

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...