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基于不溶于水和溶于水的载体的无形固体分散物的体内性能:纤维酸的案例研究

Giovanna C R M Schver1, Jasmina Novakovic2, Ping I Lee1

  • 1Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario M5S 3M2, Canada.

International journal of pharmaceutics
|January 20, 2025
PubMed
概括

无形固体分散 (ASDs) 可以增强芬纤维酸 (FNB) 的生物可用性. 最佳吸收取决于超和率,适度下降对药物暴露有益.

关键词:
吸收模拟的吸收模型无形固体的分散性固体.生物可用性 生物可用性剂量影响剂量效应.菲诺纤维酸盐的使用方法动力溶解性 动力溶解性菲马公司的水凝.在PVA中使用PVA.在PVP中,PVP是PVP.超和率是指超和率是指超和率.

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