在功能良好的老年人中,强度抵抗训练对骨形成提供了短期的好处
Mads Bloch-Ibenfeldt1, Anne Theil Gates1, Niklas Rye Jørgensen2
1Institute of Sports Medicine Copenhagen (ISMC), Department of Orthopedic Surgery M81, Copenhagen University Hospital - Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Denmark; Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
Bone
|January 20, 2025
概括
重力训练在老年人中短暂地促进了骨的形成,但不会长期影响骨矿物质密度. 这项研究探讨了阻力训练对老化骨健康的影响.
科学领域:
- 老年学和运动科学
- 骨代谢和健康 骨代谢和健康
- 老龄化和肌肉骨健康问题
背景情况:
- 保持骨健康对于老年人独立生活至关重要.
- 建议进行多式运动,包括举重活动,以保持骨健康.
- 抵抗训练强度对骨健康的影响需要进一步研究.
研究的目的:
- 为了确定一年的不同强度的受监督的力量训练是否会对老年人骨健康产生积极影响.
- 为了比较重力训练 (HRT) 和中等强度训练 (MIT) 与对照组的影响.
主要方法:
- 451名老年人 (平均年龄66岁) 被随机分配到HRT,MIT或对照组1年.
- 使用DXA测量骨矿物质密度 (BMD);评估骨循环标志物 (CTX,PINP) 和维生素K状态 (dp-ucMGP).
- 测量是在基线,第一年进行的,并在第二年和第四年进行的随访.
主要成果:
- 骨髓质量在不同组之间没有显著变化,并且在4年内在全身和大腿部下降.
- 重力训练 (HRT) 显示,在1年后,骨形成标志物PINP的短期增加.
- 随着时间的推移,骨再吸收标记CTX在所有组中都增加;dp-ucMGP保持稳定.
结论:
- 一年重力训练 (HRT) 对老年人骨形成产生了积极的短期影响.
- 这种对骨生物标志物的影响没有长期持续,也没有转化为骨质量变化.
- 耐力训练强度可能对这个人群的骨密度长期影响有限.
相关概念视频
01:29Bone Disorders
3.4K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.4K
01:27Exercise and Muscle Performance
1.3K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
1.3K
01:40Bone Remodeling
38.1K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
38.1K
01:17Hormones and Bone Tissue
2.6K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.6K
01:31Osteoclasts in Bone Remodeling
2.8K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
2.8K
01:25Role of Vitamins in Maintaining Bone Health
3.1K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.1K