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芬兰霍奇金淋巴瘤发病率和患病率的增加:基于人口的注册研究

Tessa Antikainen¹, Noora Hannuksela¹, Anna Anttalainen²

¹Faculty of Health Medicine, School of Medicine, Institute of Clinical Medicine Oncology, University of Eastern Finland, Kuopio, Finland.

European journal of public health

|January 20, 2025

概括

霍奇金 (Hodgkin) 是一个著名的作家.

科学领域:

流行病学流行病学
血液学血液学血液学
在瘤学瘤学.

背景情况:

霍奇金淋巴瘤 (HL) 是一种显著的淋巴细胞恶性瘤.
在发达国家,HL的发病率明显高于发达国家.
了解HL的流行病学趋势对于公共卫生战略至关重要.

研究的目的:

分析芬兰霍奇金淋巴瘤的流行病学变化.
为了比较年轻和老年患者队列之间的发病率和流行趋势.
与斯堪的纳维亚邻国相比,调查导致芬兰HL发病率较高的潜在因素.

主要方法:

利用了2000-2019年全国医疗保健注册表数据.
包括2912名与对照组匹配的霍奇金淋巴瘤患者.
通过将患者分为年轻 (<50岁) 和年长 (≥50岁) 的队列来分析数据.

主要成果:

在各个年龄组中观察到霍奇金淋巴瘤发病率略有增加的趋势.
年轻男性 (3.19) 和女性 (2.89),年长男性 (3.07) 和女性 (1.59) 的报告平均年发病率.
记录了HL患病率的显著增加,特别是在30-50岁的女性中.

结论:

在芬兰,霍奇金淋巴瘤发病率略有上升.
霍奇金淋巴瘤的患病率正在增加,具有特定的人口结构模式.
改善疾病管理导致霍奇金淋巴瘤幸存者的比例越来越高.

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