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Updated: Jun 1, 2025

An Optogenetic Method to Control and Analyze Gene Expression Patterns in Cell-to-cell Interactions
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An Optogenetic Method to Control and Analyze Gene Expression Patterns in Cell-to-cell Interactions

Published on: March 22, 2018

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基于光素的SynNotch适配器用于调节基因表达对各种细胞外和矩阵基线索的反应

Jeremy C Tran1,2, Christopher J Kuffner1,2, Alexander M Marzilli1,2

  • 1Department of Biomedical Engineering, Boston University, Boston, MA, USA.

Nature communications
|January 20, 2025
PubMed
概括

研究人员开发了一种新的方法来控制使用光素的合成 (SynNotch) 信号传输. 这一进步使得基因表达和细胞反应能够通过时空和微环境控制来精确调节.

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相关概念视频

Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
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