成年人体质指数与低骨肌肉质量之间的关系基于NHANES 2011-2018年
Rong-Zhen Xie1,2, Xu-Song Li3, Fang-Di Zha4
1Department of Orthopaedics & Traumatology, The First Affiliated Hospital of Zhejiang Chinese Medical University, 54 Youdian Road, Shangcheng District, Hangzhou, 310006, China.
Scientific reports
|January 20, 2025
概括
较低的体重指数 (BMI) 与较高的肉症风险有关,定义为肌肉质量和功能下降. 较高的BMI似乎具有保护性,强调在肌肉健康管理中需要对BMI进行监测.
科学领域:
- 老年学是一门学科.
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 标志着肌肉质量和功能丧失的萨尔科佩尼亚,随着年龄的增长,越来越令人担忧,影响健康结果.
- 身体质量指数 (BMI) 是一个常见的健康指标,但它与肉症的复杂关系需要进一步调查.
- 了解与肉类相关的因素对于制定有效的预防和管理策略至关重要.
研究的目的:
- 研究身体质量指数 (BMI) 与大量成年人群中低肌肉质量的患病率之间的关联.
- 确定改变BMI与低肌肉质量之间的关系的人口和临床因素.
- 为了告知临床实践关于BMI在评估肉症风险中的作用.
主要方法:
- 从2011-2018年NHANES队列 (年龄≥20岁) 中对7,455名成年人的横截面分析.
- 使用尾骨肌肉质量 (DXA标准) 诊断的低肌肉质量.
- 根据年龄,性别,种族,社会经济地位和慢性疾病调整的加权多变量后勤回归.
主要成果:
- 较低的BMI与较低肌肉质量增加的几率显著相关 (调整后OR:0.508).
- 较高的BMI表明对低肌肉质量有保护作用.
- 低肌肉质量的独立风险因素包括年龄,女性性别,糖尿病和酒精消费. 与非西班牙裔白人相比,非西班牙裔黑人个体的风险较低.
结论:
- 体重指数与低肌肉质量的患病率相反相关;较低的体重指数增加了风险.
- 对BMI的临床监测对于识别患有肉症风险的个体很重要.
- 治疗肉类症需要解决多因素风险概况,包括BMI和其他临床因素.
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