评估在韩国不利用已故捐赠脏的情况
Suhyun Oh1, Keonhwa Kim1, Omi Na1
1Division of Nephrology, Department of Internal Medicine, College of Medicine, Yonsei University Severance Hospital, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Scientific reports
|January 20, 2025
概括
尽量减少已故捐赠脏的丢弃是非常重要的,因为脏疾病的末期阶段正在上升. 在韩国,整体脏丢弃率为7.9%,器官损伤是主要原因. 丢弃的脏仍然可以被利用,特别是在移植等待时间长的情况下.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 移植手术 移植手术
- 公共卫生 公共卫生
背景情况:
- 末期病率的上升需要最大限度地利用器官.
- 亚洲的低死亡捐赠者率强调了尽量减少脏丢弃的重要性.
- 了解捐赠脏丢弃模式对于改善脏移植 (KT) 结果至关重要.
研究的目的:
- 调查韩国遗弃已故捐赠脏的现状和模式.
- 确定导致脏不利用的因素.
- 评估KT的结果,使用来自捐赠者的脏,其中至少有一个脏最初被认为是丢弃的.
主要方法:
- 在2013年至2018年期间,韩国对已故捐赠脏的全国性研究.
- 定义脏丢弃是没有采购或采购后丢弃.
- 分析了丢弃的原因,捐赠者的特征和移植结果.
主要成果:
- 死亡捐赠脏的整体丢弃率为7.9% (分析了5592个脏).
- 不获取和丢弃的主要原因包括器官损伤,候选体的缺失和恶性瘤.
- 非利用的风险因素包括较老的捐赠者年龄,高血压,糖尿病和特定的死亡原因.
- 使用被丢弃捐赠者的逆侧移植的移植显示了可比的移植失败和死亡率.
结论:
- 在韩国,已故捐赠脏丢弃率相对较低.
- 丢弃一个脏并不排除成功移植对侧脏.
- 尽量减少丢弃和最大化利用的策略很重要,特别是考虑到长期的移植等待列表.
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