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Updated: Jun 1, 2025

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection
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从七个主要的商业可用的选项中选择一个最佳的空间转录技术的实用指南.

Hyun Ju Lim1, Ye Wang2, Anton Buzdin3,4

  • 1UCLA Technology Center for Genomics & Bioinformatics, Department of Pathology & Laboratory Medicine, 650 Charles E Young Dr. South, Los Angeles, CA, 90095, USA.

BMC genomics
|January 20, 2025
PubMed
概括

空间转录组学为组织基因表达提供了洞察力. 本指南比较了七个平台,以帮助研究人员选择最适合他们特定需求的空间技术.

关键词:
10X的视觉度是可以看到的.10X的视野高清高清.美国CosMx SMI在GeoMx DSP中使用.麦尔斯科普 (Merscope) 是一种可以观察到的仪器.有关RNA测序的RNA测序空间转录组学 空间转录组学立体声隔离器是什么意思在Xenium中,我们可以看到Xenium.

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RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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