打击沙门氏菌:重点关注抗微生物耐药性和需要有效的疫苗接种
Junaid Nazir1,2, Tasaduq Manzoor1, Afnan Saleem1
1Division of Animal Biotechnology, Faculty of Veterinary Sciences & Animal Husbandry, SKUAST Kashmir, Shuhama, J&K, 190006, India.
BMC infectious diseases
|January 20, 2025
概括
沙门氏菌感染每年导致9500万例疾病和15万例死亡,而抗菌素耐药性构成了主要挑战. 开发有效的,广泛的疫苗对于全球公共卫生控制至关重要.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 疫苗学 疫苗学 疫苗学
背景情况:
- 沙门氏菌感染是全球重要的健康问题,原因是动物传播和抗菌素耐药性.
- 疾病和死亡率的上升需要改进的控制策略,特别是疫苗接种.
研究的目的:
- 审查沙门氏菌的动物传染性方面.
- 总结沙门氏菌对抗菌素耐药性的挑战.
- 评估沙门氏菌疫苗的全球负担和需求.
主要方法:
- 在主要的科学数据库 (PubMed,Scopus,Web of Science,Google Scholar) 进行系统的文献审查.
- 包括英语的同行评审文章,重点关注沙门氏菌流行病学,疫苗开发和控制策略.
- 不包括会议摘要和未经同行评审的研究.
主要成果:
- 全球每年约有9500万例沙门氏菌感染和15万例死亡,低收入/中等收入国家的发病率更高.
- 由于过度使用抗生素,多药耐药 (MDR) 沙门氏菌株的流行率正在增加.
- 开发各种沙门氏菌疫苗 (活体减弱,杀死,重组,亚单元,结合) 在有效性,成本和广泛覆盖方面面临挑战.
结论:
- 沙门氏菌感染对全球健康造成重大负担,而这种负担又被抗菌素耐药性所加剧.
- 迫切需要一项综合性战略,包括卫生,抗生素管理和可获得的,广泛的疫苗.
- 加强监测和国际合作对于有效控制沙门氏菌至关重要.
更多相关视频
09:59Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance
Published on: July 21, 2023
1.2K
08:19Modified Most Probable Number Assay to Quantify Salmonella in Raw and Ready-to-Cook Chicken Products
Published on: January 31, 2025
311
相关概念视频
00:57Antibiotic Selection
52.2K
Overview
52.2K
01:31Defense Against Bacterial Pathogens
1.4K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
1.4K
01:51Vaccinations
44.0K
Overview
44.0K
00:46Genomic DNA in Prokaryotes
43.4K
The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
Genomic Diversity in Bacteria
Although bacterial genomes are much...
Genomic Diversity in Bacteria
Although bacterial genomes are much...
43.4K
01:20Infection
7.6K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
7.6K